E-mail

E-mail a Wiley Online Library Link

Dr. Tiziana Marino, Prof. Nino Russo and Prof. Marirosa Toscano Catalytic Mechanism of the Arylsulfatase Promiscuous Enzyme from Pseudomonas Aeruginosa Chemistry - A European Journal 19

Version of Record online: 28 DEC 2012 | DOI: 10.1002/chem.201201943

Thumbnail image of graphical abstract

A quantum-mechanical method based on DFT was used to investigate the catalytic mechanism of the hydrolysis of the two substrates p-nitrophenyl- sulfate (PNPS) and p-nitrophenyl-phosphate (PNPP) by the promiscuous enzyme (see scheme). Calculations were carried out with the aim of highlighting eventual mechanistic differences in the catalysis of these two substrates that can validate the comparable kinetics experimentally observed.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH