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Andrea Barba-Bon, Prof. Ana M. Costero, Prof. Margarita Parra, Prof. Salvador Gil, Prof. Ramón Martínez-Máñez, Dr. Félix Sancenón, Prof. Philip A. Gale and Dr. Jennifer R. Hiscock Neutral 1,3-Diindolylureas for Nerve Agent Remediation Chemistry - A European Journal 19

Version of Record online: 23 DEC 2012 | DOI: 10.1002/chem.201202028

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Efficient neutralization of nerve-agent simulants by 1,3-diindolylureas in a neutral medium was investigated (see scheme; DCP=diethylchlorophosphate, DCNP=diethylcyanophosphonate). The rate of hydrolysis of the simulants was found to increase by as much as 45 % in the presence of these compounds. A mechanism based on the simulant complexation was established.

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