Andrea Barba-Bon, Prof. Ana M. Costero, Prof. Margarita Parra, Prof. Salvador Gil, Prof. Ramón Martínez-Máñez, Dr. Félix Sancenón, Prof. Philip A. Gale and Dr. Jennifer R. Hiscock Neutral 1,3-Diindolylureas for Nerve Agent Remediation Chemistry - A European Journal 19
Efficient neutralization of nerve-agent simulants by 1,3-diindolylureas in a neutral medium was investigated (see scheme; DCP=diethylchlorophosphate, DCNP=diethylcyanophosphonate). The rate of hydrolysis of the simulants was found to increase by as much as 45 % in the presence of these compounds. A mechanism based on the simulant complexation was established.
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