Dr. Mona A. Furrer, Amine Garci, Emmanuel Denoyelle-Di-Muro, Dr. Patrick Trouillas, Federico Giannini, Dr. Julien Furrer, Catherine M. Clavel, Prof. Dr. Paul J. Dyson, Prof. Dr. Georg Süss-Fink and Prof. Dr. Bruno Therrien Synthesis, Characterisation and In Vitro Anticancer Activity of Hexanuclear Thiolato-Bridged Arene Ruthenium Metalla-Prisms Chemistry - A European Journal 19
Version of Record online: 23 JAN 2013 | DOI: 10.1002/chem.201203712
All in the delivery! Hexanuclear thiolato-bridged arene–ruthenium metalla-prisms have been synthesised and characterised (see scheme). They are highly cytotoxic against human ovarian-cancer cells, especially towards the cisplatin-resistant cell line A2780cisR (IC50 <0.25 μM).
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