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Dr. Takanori Iwasaki, Kiyokazu Higashikawa, Dr. Vutukuri P. Reddy, Willbe W. S. Ho, Prof. Dr. Yukari Fujimoto, Prof. Dr. Koichi Fukase, Prof. Dr. Jun Terao, Prof. Dr. Hitoshi Kuniyasu and Prof. Dr. Nobuaki Kambe Nickel[BOND]Butadiene Catalytic System for the Cross-Coupling of Bromoalkanoic Acids with Alkyl Grignard Reagents: A Practical and Versatile Method for Preparing Fatty Acids Chemistry - A European Journal 19

Article first published online: 1 FEB 2013 | DOI: 10.1002/chem.201204222

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The knights who say Ni: A practical and convenient synthetic route to fatty acids involves the Ni-catalyzed alkyl[BOND]alkyl cross-coupling of bromoalkanoic acids and alkyl Grignard reagents in the presence of 1,3-butadiene as an additive (see scheme).

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