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Prof. Dr. Masayuki Endo, Masahiro Inoue, Dr. Yuki Suzuki, Chigusa Masui, Dr. Hironobu Morinaga, Kumi Hidaka and Prof. Dr. Hiroshi Sugiyama Regulation of B–Z Conformational Transition and Complex Formation with a Z-Form Binding Protein by Introduction of Constraint to Double-Stranded DNA by using a DNA Nanoscaffold Chemistry - A European Journal 19

Version of Record online: 5 NOV 2013 | DOI: 10.1002/chem.201303830

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B–Z transition: A constrained and rotatable double-stranded DNA, in which the rotational freedom was controlled by its placement into a DNA nanoscaffold, was designed (see scheme). The Z α β protein bound preferentially to the rotatable strand rather than the constrained strand, even using the same CG sequence.

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