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Benjamin Minow, Hugo de Witt and Dr. Ingo Knabben Fast Track API Manufacturing from Shake Flask to Production Scale Using a 1000-L Single-Use Facility Chemie Ingenieur Technik 85

Article first published online: 13 DEC 2012 | DOI: 10.1002/cite.201200136

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The necessity to shorten development timelines and efficiently manufacture biological drugs due to a highly increased competition on therapeutic targets, is forcing biotech companies to alter their production strategies. Single-use technologies in combination with platform processes and a pragmatic scale-up concept enable a significant reduction in timeline from lab to production.

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