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Jörg Kauling, Dr. Helmut Brod, Dr. Marc Jenne, Annette Waldhelm, Dr. Uwe Langer and Dr. Berthold Bödeker Novel, Rotary Oscillated, Scalable Single-Use Bioreactor Technology for the Cultivation of Animal Cells Chemie Ingenieur Technik 85

Article first published online: 19 DEC 2012 | DOI: 10.1002/cite.201200155

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A novel single-use bioreactor is presented that utilizes the rotary oscillation of a polyhedral container as working principle. Thereby, also highly shear sensitive cell suspensions or microcarrier cultures can be cultivated in unmatched scales by employing simple, empty, robust and cost-efficient single-use 3D-bags.

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