Stephan Kaiser, Valentin Jossen, Carmen Schirmaier, Prof. Dieter Eibl, Dr. Silke Brill, Christian van den Bos and Prof. Regine Eibl Fluid Flow and Cell Proliferation of Mesenchymal Adipose-Derived Stem Cells in Small-Scale, Stirred, Single-Use Bioreactors Chemie Ingenieur Technik 85
The fluid flow and suspension characteristics in small-scale, stirred, single-use bioreactors were investigated experimentally and numerically. The required impeller speeds for homogenous suspension and the resulting shear stress levels were determined. The microcarrier type significantly influences the impeller speed required to achieve the desired suspension characteristics.
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