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Dr. Wolfgang Hüttel Biocatalytic Production of Chemical Building Blocks in Technical Scale with α-Ketoglutarate-Dependent Dioxygenases Chemie Ingenieur Technik 85

Article first published online: 17 APR 2013 | DOI: 10.1002/cite.201300008

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In addition to the well-known P450 monooxygenases, α-ketoglutarate-dependent dioxygenases have a great potential for the catalysis of regio- and stereoselective CH-functionalizations even at the industrial scale. In this review the most important approaches for the application of this as yet scarcely employed group of enzymes are discussed.

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