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Lei Zhang, Ping Qu, Jin Sheng, Jianping Lei and Huangxian Ju Open Tubular Microreactor with Enzyme Functionalized Microfluidic Channel for Amperometric Detection of Glucose Chinese Journal of Chemistry 30

Version of Record online: 25 SEP 2012 | DOI: 10.1002/cjoc.201200725

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A simple and efficient enzyme microreactor was designed for amperometric detection of glucose. The open tubular microreactor was composed of a polydimethylsilicone/glass hybrid device with three reservoirs, a cooling cave and a 6-cm capillary with a sampling fracture as microchannel. The microchannel was modified by thermal polymerization, followed by covalently attaching with glucose oxidase. The designed microreactor showed good sensitivity, rapid separation and acceptable stability and reproducibility, and was successfully used for quantitative determination of glucose in real sample.

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