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Jie Zhang, Shijun Da, Xiaolin Feng, Xiaoyi Chen, Jianhui Jiang and Ying Li First Total Synthesis of the Proposed Structures of Orisuaveolines A and B Chinese Journal of Chemistry 31

Version of Record online: 8 JAN 2013 | DOI: 10.1002/cjoc.201200986

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First total synthesis of the proposed structures of β-indoloquinazoline alkaloids orisuaveolines A and B is reported. The key steps of the synthesis included a Pictet-Spengler reaction to build a six-member lactam which further transformed into target molecular by a one-pot condensation. The structures of our synthesized products were confirmed by 2D-NMR experiments.

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