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Aurélie Blond, Dr. Eric Ennifar, Dr. Carine Tisné and Dr. Laurent Micouin The Design of RNA Binders: Targeting the HIV Replication Cycle as a Case Study ChemMedChem 9

Article first published online: 5 AUG 2014 | DOI: 10.1002/cmdc.201402259

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Interfering at the RNA level: The HIV-1 replication cycle is finely tuned with many important steps involving RNA–RNA or protein–RNA interactions, all of them being potential targets for the development of new antiviral compounds. This review highlights approaches developed to interfere with four important steps of the HIV-1 replication cycle.

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