E-mail a Wiley Online Library Link

Hoe Suk Kim, Lianji Tian, Shunmei Lin, Joo Hee Cha, Hye Seung Jung, Kyong Soo Park and Woo Kyung Moon Magnetic labeling of pancreatic β-cells modulates the glucose- and insulin-induced phosphorylation of ERK1/2 and AKT Contrast Media & Molecular Imaging 8

Version of Record online: 29 OCT 2012 | DOI: 10.1002/cmmi.1490

Thumbnail image of graphical abstract

SPIO labeling results in an increase in the phosphorylation levels of ERK1/2 and AKT, but the significant decrease in the glucose– and insulin–stimulated phosphorylation of AKT and glucose–stimulated phosphorylation of ERK1/2 and which caused a reduction in the insulin produced upon stimulation with glucose or insulin. SPIO labeling could influence the function of pancreatic β–cells through modulation of the glucose– or insulin–induced activation of ERK1/2 and AKT that leads to insulin biosynthesis.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field