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Emilie Bled, Wadie Ben Hassen, Line Pourtau, Philippe Mellet, Titus Lanz, Dorothee Schüler, Pierre Voisin, Jean-Michel Franconi, Eric Thiaudière and Sylvain Miraux Real-time 3D MRI of contrast agents in whole living mice Contrast Media & Molecular Imaging 6

Version of Record online: 2 FEB 2011 | DOI: 10.1002/cmmi.429

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A specific mouse whole body coil and a dedicated gradient system at 4.7T are coupled with an ultra-fast 3D gradient echo MRI and keyhole reconstruction technique to obtain 3D whole body dynamic T1-weighted or T2*-weighted imaging. The technique is used to visualize the real-time distribution of non-targeting T1 and T2* contrast agent in a glioma-bearing mouse model.

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