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Xiaohui Wei, Jiong Zhu, Hongxia Gong, Jianrong Xu and Yuhong Xu A novel foam fluid negative contrast medium for clear visualization of the colon wall in CT imaging Contrast Media & Molecular Imaging 6

Version of Record online: 29 NOV 2011 | DOI: 10.1002/cmmi.446

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A novel foam fluid negative contrast medium for colon CT imaging was prepared by dispersing a large number of air bubbles in a polymeric solution. Both the stabilities of the individual bubbles and the foam fluid system were optimized by incorporating BSA and gluconolactone as the stabilization agent. Such an oil free contrast medium had a mean x-ray density of −120HU, which resulted in a “dark lumen” effect and enabled the clear 2D visualization of the colonic wall.

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