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N. Volkan Adsay, Kevin C. Conlon, Sui Y. Zee, Murray F. Brennan and David S. Klimstra Intraductal papillary-mucinous neoplasms of the pancreas Cancer 94

Article first published online: 28 DEC 2001 | DOI: 10.1002/cncr.10203

Both in situ and invasive carcinoma in pancreatic intraductal papillary-mucinous neoplasms (IPMNs) may be more common than previously recognized. Colloid (mucinous) carcinomas and tubular carcinomas occur that resemble conventional ductal adenocarcinomas. Although they are less aggressive as a group than ductal adenocarcinomas, IPMNs may pursue a deadly course, even in the absence of identifiable invasive carcinoma. Conversely, patients with invasive tubular carcinomas arising from IPMNs may have a more favorable clinical course than patients with ductal adenocarcinomas without an IPMN component.

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