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Kazuya Kondo, Yuji Takahashi, Sumiyo Ishikawa, Hiroshi Uchihara, Yukiko Hirose, Kiyoshi Yoshizawa, Masaru Tsuyuguchi, Hiromitsu Takizawa, Takanori Miyoshi, Shoji Sakiyama and Yasumasa Monden Microscopic analysis of chromium accumulation in the bronchi and lung of chromate workers Cancer 98

Article first published online: 14 OCT 2003 | DOI: 10.1002/cncr.11818

The authors microscopically evaluated the accumulation of chromium in 10 resected lung tissue specimens and 90 biopsy specimens from chromate workers. Chromium accumulation in the proximal bronchi was less than in the bronchioles or subpleural regions of the lung. In addition, chromium accumulation increased significantly according to the progression of malignant change of the bronchial epithelium.

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