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Jonas Hugosson, Gunnar Aus, Hans Lilja, Pär Lodding and Carl-Gustav Pihl Results of a randomized, population-based study of biennial screening using serum prostate-specific antigen measurement to detect prostate carcinoma Cancer 100

Version of Record online: 4 MAR 2004 | DOI: 10.1002/cncr.20126

The authors evaluated the effectiveness of a prostate carcinoma screening program in which serum prostate-specific antigen (PSA) levels were measured. Biennial PSA screening was found to be very successful in diagnosing prostate carcinoma at an early stage, and the results regarding interval malignancies also were favorable. In addition, the lead time associated with screening in the current study appears to fall within the range described in earlier studies involving frozen sera (i.e., 5–9 years).

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