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Cordelia Luyken, Ingmar Blümcke, Rolf Fimmers, Horst Urbach, Otmar D. Wiestler and Johannes Schramm Supratentorial gangliogliomas: Histopathologic grading and tumor recurrence in 184 patients with a median follow-up of 8 years Cancer 101

Version of Record online: 28 MAY 2004 | DOI: 10.1002/cncr.20332

Over a median follow-up period of 8 years, tumor recurrence was identified in only 3% of 184 patients with supratentorial gangliogliomas. However, malignant progression (2%) and death (1%) also were encountered. A favorable prognosis was associated with Grade 1 disease according to the World Health Organization classification system. Tumor location within the temporal lobe, complete resection of the lesion, and chronic seizures were additional parameters that predicted a favorable outcome after neurosurgical therapy.

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