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Elena B. Elkin, Clifford Hudis, Colin B. Begg and Deborah Schrag The effect of changes in tumor size on breast carcinoma survival in the U.S.: 1975–1999 Cancer 104

Version of Record online: 8 AUG 2005 | DOI: 10.1002/cncr.21285

Over the past 30 years, the distribution of incident breast carcinoma cases in the U.S. has shifted toward smaller tumors, even within conventional stage categories. A substantial proportion of the improvement noted in breast carcinoma survival can be attributed to this within-stage migration of tumor size. Standardizing survival estimates on the basis of tumor size improves the understanding of secular trends in breast carcinoma outcomes.

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