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Tae Hyun Kim, Jinho Choi, Sung-Yong Park, Seok-Ho Lee, Kyu-Chan Lee, Dae Sik Yang, Kyung Hwan Shin, Kwan Ho Cho, Hyun-Sun Lim and Joo-Young Kim Dosimetric parameters that predict late rectal complications after curative radiotherapy in patients with uterine cervical carcinoma Cancer 104

Version of Record online: 2 AUG 2005 | DOI: 10.1002/cncr.21292

The 5-year actuarial rate of late rectal complication (LRC) ≥ Grade 2 was 5.4% in patients who received a total biologically effective dose (BED) at rectal point (BEDRP) < 125 Gy3 and 36.1% in patients who received a BEDRP ≥ 125 Gy3 (P < 0.001). The BEDRP was a useful dosimetric parameter for predicting the risk of LRC ≥ Grade 2 and should be limited to < 125 Gy3 whenever possible to minimize the risk of LRC ≥ Grade 2 in patients with uterine cervical carcinoma who are treated with a combination of external beam radiotherapy and high-dose-rate intracavitary irradiation.

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