E-mail

E-mail a Wiley Online Library Link

Emer O. Hanrahan, Kristine R. Broglio, Aman U. Buzdar, Richard L. Theriault, Vicente Valero, Massimo Cristofanilli, Guosheng Yin, Shu-Wan C. Kau, Gabriel N. Hortobagyi and Edgardo Rivera Combined-modality treatment for isolated recurrences of breast carcinoma Cancer 104

Article first published online: 26 JUL 2005 | DOI: 10.1002/cncr.21305

Patients with an isolated recurrence of breast carcinoma that has been treated locally with surgical resection and/or irradiation with curative intent, such that there is no evidence of clinically measurable disease are classified as Stage IV—no evidence of disease (Stage IV-NED). Compared with historic controls, these patients demonstrated improved outcomes in Phase II studies if they received systemic chemotherapy after local treatment for their isolated recurrence. A proportion of these patients with Stage IV-NED breast carcinoma had prolonged disease-free and overall survival after chemotherapy, and the only significant independent prognostic factor was the number of involved axillary lymph nodes at initial diagnosis.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH