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Masahiro Kobayashi, Kenji Ikeda, Tetsuya Hosaka, Hitomi Sezaki, Takashi Someya, Norio Akuta, Fumitaka Suzuki, Yoshiyuki Suzuki, Satoshi Saitoh, Yasuji Arase and Hiromitsu Kumada Dysplastic nodules frequently develop into hepatocellular carcinoma in patients with chronic viral hepatitis and cirrhosis Cancer 106

Article first published online: 20 DEC 2005 | DOI: 10.1002/cncr.21607

High-grade dysplastic nodules should be considered precancerous lesions when they appear during clinical observation of chronic viral hepatitis or cirrhosis. Decreased portal blood flow in the nodule on CT-AP is an important predictor for development of hepatocellular carcinoma.

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