Cristina Garcia-Aranda, Carmen de Juan, Antonio Diaz-Lopez, Andres Sanchez-Pernaute, Antonio-Jose Torres, Eduardo Diaz-Rubio, Jose-Luis Balibrea, Manuel Benito and Pilar Iniesta Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma Cancer 106
Version of Record online: 30 DEC 2005 | DOI: 10.1002/cncr.21625
Data from this study indicated that, among patients with colorectal carcinoma who had tumors that displayed telomerase reactivation, only those who had tumors with telomere elongation had a poor prognosis. Moreover, telomerase-positive colorectal tumors that over-expressed telomeric-repeat binding factor 1 had telomere shortening, and patients with those tumors had a better clinical course.
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