Federica Sorá, Nicola Piccirillo, Patrizia Chiusolo, Luca Laurenti, Roberto Marra, Francesco Bartolozzi, Giuseppe Leone and Simona Sica Mitoxantrone, carboplatin, cytosine arabinoside, and methylprednisolone followed by autologous peripheral blood stem cell transplantation Cancer 106
Article first published online: 17 JAN 2006 | DOI: 10.1002/cncr.21634
A salvage chemotherapy regimen consisting of mitoxantrone, carboplatin, cytosine arabinoside, and methylprednisolone (MiCMA) was adopted for the treatment of 94 patients with primary refractory or recurrent non-Hodgkin lymphoma. The study results demonstrated that MiCMA is an effective therapeutic alternative salvage regimen in this setting. Response rates, overall survival, and freedom from disease progression all were found to be associated significantly with response to MiCMA.
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