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Timothy M. Pawlik, Merrick I. Ross, Victor G. Prieto, Matthew T. Ballo, Marcella M. Johnson, Paul F. Mansfield, Jeffrey E. Lee, Janice N. Cormier and Jeffrey E. Gershenwald Assessment of the role of sentinel lymph node biopsy for primary cutaneous desmoplastic melanoma Cancer 106

Article first published online: 12 JAN 2006 | DOI: 10.1002/cncr.21635

The role of sentinel lymph node biopsy (SLNB) in the treatment of desmoplastic melanoma (DM) remains undefined. The authors report that patients with a pure DM histologic subtype have a lower incidence of positive SLNs compared with patients who have mixed DM or non-DM melanomas. Whereas patients with mixed DM should be treated like all other melanoma patients, patients with pure DM are unlikely to have metastatic disease in regional lymph nodes and SLNB may not be warranted.

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