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Ayalew Tefferi, Terra L. Lasho, Susan M. Schwager, Jacob S. Strand, Michelle Elliott, Ruben Mesa, Chin-Yang Li, Martha Wadleigh, Stephanie J. Lee and D. Gary Gilliland The clinical phenotype of wild-type, heterozygous, and homozygous JAK2V617F in polycythemia vera Cancer 106

Article first published online: 20 DEC 2005 | DOI: 10.1002/cncr.21645

Several studies have recently reported on the occurrence of a JAK2V617F mutation in myeloid cells from the majority of patients with polycythemia vera (PV). In a single institutional study, mutation screening for JAK2V617F was performed in DNA derived from archived blood granulocytes from 63 consecutive patients with PV in whom current diagnostic criteria were strictly applied and the diagnosis confirmed by bone marrow histology.

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