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Katarina Shahedi, Monica Emanuelsson, Fredrik Wiklund and Henrik Gronberg High risk of contralateral breast carcinoma in women with hereditary/familial non-BRCA1/BRCA2 breast carcinoma Cancer 106

Version of Record online: 13 FEB 2006 | DOI: 10.1002/cncr.21753

In this investigation, the risk of developing contralateral breast carcinoma (CBC) was found to be high among women in northern Sweden who had hereditary/familial non-BRCA1/BRCA2 breast carcinoma. The high risk of developing CBC was attenuated further among women who were younger at the time of diagnosis (<50 years). This group had a cumulative probability of developing CBC of nearly 40% after 15 years, which was similar to the estimated risk among BRCA1/BRCA2 mutation carriers.

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