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Mieke Kriege, Cecile T. M. Brekelmans, Carla Boetes, Sara H. Muller, Harmine M. Zonderland, Inge Marie Obdeijn, Radu A. Manoliu, Theo Kok, Emiel J. T. Rutgers, Harry J. de Koning, Jan G. M. Klijn and Dutch MRI Screening (MRISC) Study Group Differences between first and subsequent rounds of the MRISC breast cancer screening program for women with a familial or genetic predisposition Cancer 106

Version of Record online: 13 APR 2006 | DOI: 10.1002/cncr.21863

In the Dutch magnetic resonance imaging (MRI) breast cancer screening study for women with a hereditary risk, a higher sensitivity and a better discriminating capacity of MRI compared with mammography was maintained in subsequent rounds. Also, favorable characteristics of tumors detected during these subsequent rounds were maintained compared with those of age-matched controls. This is reassuring, because results of these subsequent screening rounds were most predictive for long-term effects.

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