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Patricia Harnden, Michael D. Shelley, Hayley Clements, Bernadette Coles, R. Sandy Tyndale-Biscoe, Brian Naylor and Malcolm D. Mason The prognostic significance of perineural invasion in prostatic cancer biopsies Cancer 109

Version of Record online: 22 NOV 2006 | DOI: 10.1002/cncr.22388

The weight of evidence favors a significant association between perineural invasion in prostatic biopsies and risk of recurrence after radical treatment particularly in a subgroup of patients selected on the basis of presenting serum PSA and biopsy Gleason score. The standards of study design and execution are insufficient to assess the magnitude of this risk.

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