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Rubén Cabanillas, Juan Pablo Rodrigo, Aurora Astudillo, Francisco Domínguez, Carlos Suárez and Maria Dolores Chiara P53 expression in squamous cell carcinomas of the supraglottic larynx and its lymph node metastases Cancer 109

Version of Record online: 22 MAR 2007 | DOI: 10.1002/cncr.22646

The objective of this study was to investigate the expression pattern and prognostic significance of p53 expression in head and neck squamous cell carcinomas (SCCs) of the same location, treated in the same way, and with long-term follow-up. The results indicated that p53 overexpression in the lymph node metastases from SCCs of the supraglottic larynx was an independent predictor of regional failure and a poor prognosis.

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