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Perry J. Pickhardt, Cesare Hassan, Andrea Laghi, Angelo Zullo, David H. Kim and Sergio Morini Cost-effectiveness of colorectal cancer screening with computed tomography colonography Cancer 109

Article first published online: 23 APR 2007 | DOI: 10.1002/cncr.22668

Prior cost-effectiveness models analyzing computed tomography colonography (CTC) screening have assumed that patients with lesions measuring ≤5 mm will be referred to optical colonoscopy for polypectomy. However, consensus guidelines for CTC recommend reporting only those polyps that are ≥6 mm in size. The purpose of the current study was to assess the potential harms, benefits, and cost-effectiveness of CTC screening without the reporting of diminutive lesions compared with other screening strategies.

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