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Wunchana Seubwai, Chaisiri Wongkham, Anucha Puapairoj, Narong Khuntikeo and Sopit Wongkham Overexpression of vitamin D receptor indicates a good prognosis for cholangiocarcinoma Cancer 109

Article first published online: 8 MAY 2007 | DOI: 10.1002/cncr.22716

Overexpression of VDR is associated with tumor development and better survival of cholangiocarcinoma patients. The antiproliferative effects of 1,25(OH)2D3 in cholangiocarcinoma cell lines appear to be mediated by VDR, thus suggesting a use for vitamin D or its analogs in treatment of cholangiocarcinoma.

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