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Cary P. Gross, Gail J. McAvay, Zhenchao Guo and Mary E. Tinetti The impact of chronic illnesses on the use and effectiveness of adjuvant chemotherapy for colon cancer Cancer 109

Version of Record online: 17 MAY 2007 | DOI: 10.1002/cncr.22726

Among older patients who underwent surgical resection for stage III colon cancer, the receipt of adjuvant therapy was related significantly to heart failure (36.2% vs 64.9% of patients with and without heart failure, respectively) and chronic obstructive pulmonary disease (COPD) (55.2% vs 61.5% of patients with and without COPD, respectively). The current results also indicated that these conditions adversely altered the risks and benefits of adjuvant therapy, suggesting that chronic conditions may affect patterns of cancer care in a manner that does not reflect their relation to clinical effectiveness.

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