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Vladimir F. Semiglazov, Vladislav V. Semiglazov, Garik A. Dashyan, Elena K. Ziltsova, Vadim G. Ivanov, Alla A. Bozhok, Olga A. Melnikova, Ruslan M. Paltuev, Alexander Kletzel and Lev M. Berstein Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor-positive breast cancer Cancer 110

Article first published online: 30 MAY 2007 | DOI: 10.1002/cncr.22789

This phase 2 randomized controlled trial evaluated the efficacy of neoadjuvant treatment with aromatase inhibitors compared with neoadjuvant chemotherapy in postmenopausal women with hormone receptor-positive breast cancer. Aromatase inhibitors were well tolerated, and rates of overall objective response and breast-conserving surgery were similar in both treatment groups.

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