Yuanqing Ye, Hushan Yang, H. Barton Grossman, Colin Dinney, Xifeng Wu and Jian Gu Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer Cancer 112
Article first published online: 24 MAR 2008 | DOI: 10.1002/cncr.23472
Ten single nucleotide polymorphisms from 7 cell cycle control genes were assessed on bladder cancer risk in a case-control study. The results highlight the necessity of performing pathway-based polygenetic studies that can better reveal the genetic influences on cancer susceptibilities through consideration of higher-order interactions among multiple risk elements.
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