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James B. Yu, Lynn D. Wilson, Tina Dasgupta, William A. Castrucci and Joanne B. Weidhaas Postmastectomy radiation therapy for lymph node-negative, locally advanced breast cancer after modified radical mastectomy Cancer 113

Version of Record online: 28 APR 2008 | DOI: 10.1002/cncr.23512

This National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results (SEER) database study shows that postoperative radiation therapy does not appear to improve overall survival for T3N0 breast cancer after modified radical mastectomy. The study does identify higher-risk subsets of patients that may benefit from postoperative radiation in terms of local control, which could not be studied in SEER.

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