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Jill Gilbert, Anthony Cmelak, Yu Shyr, James Netterville, Brian B. Burkey, Robert J. Sinard, Wendall G. Yarbrough, Christine H. Chung, Joseph M. Aulino and Barbara A. Murphy Phase II trial of irinotecan plus cisplatin in patients with recurrent or metastatic squamous carcinoma of the head and neck Cancer 113

Article first published online: 16 MAY 2008 | DOI: 10.1002/cncr.23545

The combination of irinotecan and cisplatin is an active regimen in metastatic or recurrent squamous cell carcinoma of the head and neck. However, this combination of drugs is associated with significant toxicities.

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