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Wolfram E. Samlowski, Martin Majer, Kenneth M. Boucher, Annabelle F. Shrieve, Christopher Dechet, Randy L. Jensen and Dennis C. Shrieve Multidisciplinary treatment of brain metastases derived from clear cell renal cancer incorporating stereotactic radiosurgery Cancer 113

Article first published online: 8 SEP 2008 | DOI: 10.1002/cncr.23857

Brain metastases are a frequent and adverse complication in metastatic clear cell renal cancer. The aggressive treatment of patients with renal cancer brain metastases incorporating stereotactic radiosurgery (SRS) and subsequent systemic therapy resulted in prolonged survival in 16% of patients. The best outcome was obtained in ‘good-risk’ patients treated with interleukin-2-based immunotherapy after SRS.

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