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Aleodor A. Andea, Daniel G. Coit, Bijal Amin and Klaus J. Busam Merkel cell carcinoma Cancer 113

Article first published online: 16 SEP 2008 | DOI: 10.1002/cncr.23874

In this study, the authors performed a retrospective review of histologic parameters and clinical outcome data in a series of 156 patients with a diagnosis of Merkel cell carcinoma. The results revealed that, in a multivariate analysis, in addition to the known prognostic value of tumor stage, 3 histologic features were independent predictors of survival: tumor thickness, the presence of lymphatic tumor emboli, and tumor growth pattern.

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