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Alejandro Forner, Carmen Ayuso, María Varela, Jordi Rimola, Amelia J. Hessheimer, Carlos Rodriguez de Lope, María Reig, Luís Bianchi, Josep M. Llovet and Jordi Bruix Evaluation of tumor response after locoregional therapies in hepatocellular carcinoma Cancer 115

Article first published online: 30 DEC 2008 | DOI: 10.1002/cncr.24050

The objective of this study was to compare the concordance/agreement of tumor response evaluated by Response Evaluation Criteria in Solid Tumors (RECIST) versus European Association for the Study of the Liver guidelines in a cohort of patients who received locoregional therapy, including percutaneous ablation (by ethanol injection or radiofrequency) and transarterial chemoembolization, for hepatocellular carcinoma. The results indicated that RECIST has no value in this assessment of tumor response after locoregional therapies in patients with hepatocellular carcinoma and this evaluation should incorporate the reduction in viable tumor burden as recognized by nonenhanced areas by dynamic imaging studies.

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