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Enrique Carrillo de Santa Pau, Fernando Carrillo Arias, Enrique Caso Peláez, Gemma María Muñoz Molina, Ignacio Sánchez Hernández, Ignacio Muguruza Trueba, Ramón Moreno Balsalobre, Silvia Sacristán López, Alejandro Gómez Pinillos and María del Val Toledo Lobo Prognostic significance of the expression of vascular endothelial growth factors A, B, C, and D and their receptors R1, R2, and R3 in patients with nonsmall cell lung cancer Cancer 115

Article first published online: 5 FEB 2009 | DOI: 10.1002/cncr.24193

The authors analyzed expression of the vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) family of proteins and survival in patients with nonsmall cell lung cancer (NSCLC). The results indicated that the overexpression of VEGFs and VEGFRs plays an important role in the survival of patients with NSCLC, and the inclusion of angiogenic factors in the standard pathologic study of lung cancer may improve the clinical evaluation of patients with NSCLC.

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