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Catherine Liebig, Gustavo Ayala, Jonathan A. Wilks, David H. Berger and Daniel Albo Perineural invasion in cancer Cancer 115

Article first published online: 29 MAY 2009 | DOI: 10.1002/cncr.24396

Perineural invasion is emerging as an important prognostic feature in many malignancies, yet much remains to be understood about this pathologic process. For this review, the authors set forth a clear definition of perineural invasion and summarized the current literature regarding its clinical significance, molecular pathogenesis, and areas of targeted research.

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