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Takefumi Satoh, Masaki Kimura, Kazumasa Matsumoto, Ken-ichi Tabata, Hiroshi Okusa, Hideharu Bessho, Masatsugu Iwamura, Hiromichi Ishiyama, Kazushige Hayakawa and Shiro Baba Single infusion of zoledronic acid to prevent androgen deprivation therapy-induced bone loss in men with hormone-naive prostate carcinoma Cancer 115

Article first published online: 29 MAY 2009 | DOI: 10.1002/cncr.24404

A single infusion of zoledronic acid increased bone mineral density and decreased urine N-telopeptide levels in hormone-naive patients with prostate carcinoma. These effects were durable within 12 months after the initiation of androgen-deprivation therapy.

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