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Celestia S. Higano, Paul F. Schellhammer, Eric J. Small, Patrick A. Burch, John Nemunaitis, Lianng Yuh, Nicole Provost and Mark W. Frohlich Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer Cancer 115

Version of Record online: 17 JUN 2009 | DOI: 10.1002/cncr.24429

The integrated results of 2 randomized studies demonstrate a survival benefit for patients treated with sipuleucel-T compared with those treated with placebo. The generally modest toxicity profile, coupled with the survival benefit, suggests a favorable risk-benefit ratio for sipuleucel-T in patients with advanced prostate cancer.

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