E-mail a Wiley Online Library Link

Jonathan D. Schwartz, Eric K. Rowinsky, Hagop Youssoufian, Bronislaw Pytowski and Yan Wu Vascular endothelial growth factor receptor-1 in human cancer Cancer 116

Version of Record online: 2 FEB 2010 | DOI: 10.1002/cncr.24789

Vascular endothelial growth factor receptor-1 (VEGFR-1) mediated signaling contributes to cancer pathogenesis by means of both direct growth stimulation and activation of endothelial, stromal, progenitor, and other cells. Antibody-mediated inhibition of VEGFR-1 represents a promising anti-cancer strategy and preliminary clinical studies investigating IMC-18F1 in humans indicate a favorable safety profile.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field