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Michael Garkavij, Mattias Nickel, Katarina Sjögreen-Gleisner, Michael Ljungberg, Tomas Ohlsson, Karin Wingårdh, Sven-Erik Strand and Jan Tennvall 177Lu-[DOTA0,Tyr3] octreotate therapy in patients with disseminated neuroendocrine tumors: Analysis of dosimetry with impact on future therapeutic strategy Cancer 116

Article first published online: 2 FEB 2010 | DOI: 10.1002/cncr.24796

Three different methods were used to evaluate the absorbed dose to the kidneys in patients with disseminated neuroendocrine tumors treated with 177Lu-(DOTA0,Tyr3) octreotate. Dosimetry based on planar images generally gave higher absorbed dose values compared with methods including single-photon emission computed tomography (SPECT) data. Two different SPECT-based methods gave similar values, although the calculations were based on different assumptions.

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