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Wendy A. Woodward, Bisrat G. Debeb, Wei Xu and Thomas A. Buchholz Overcoming radiation resistance in inflammatory breast cancer Cancer 116

Version of Record online: 19 MAY 2010 | DOI: 10.1002/cncr.25173

The clinical-pathological features of inflammatory breast cancer include enrichment of factors that have been previously associated with radioresistant disease, including negative hormone receptor status and a phenotype enriched for relatively radioresistant breast cancer stem/progenitor cells. The prevalent basal phenotype of inflammatory breast cancer makes it an ideal clinical model to examine stem cell hypotheses, which the authors believe can help guide future trials to continue making incremental progress against this aggressive disease.

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