E-mail a Wiley Online Library Link

Pier Luigi Zinzani, Alessandro Broccoli, Vittorio Stefoni, Gerardo Musuraca, Elisabetta Abruzzese, Amalia De Renzo, Maria Cantonetti, Francesco Bacci, Michele Baccarani and Stefano A. Pileri Immunophenotype and intermediate-high international prognostic index score are prognostic factors for therapy in diffuse large B-cell lymphoma patients Cancer 116

Version of Record online: 24 AUG 2010 | DOI: 10.1002/cncr.25307

This study investigated the role of immunohistochemical discrimination between germinal center B-cell (GCB) and activated B-cell and not classified (ABC&NC) diffuse large B-cell lymphoma (DLBCL) subtypes in identifying those high-risk patients who may benefit from a more aggressive first-line therapeutic approach. The authors determined that an autologous stem cell transplantation consolidation in the ABC&NC-DLBCL subtypes induces the same rate of complete response and similar progression-free survival rate compared with GCB-DLBCL. In ABC&NC-DLBCL patients, the authors observed a complete response rate of 89.7% versus 84.6% reported in GCB-DLBCL subset, without any significant difference in progression-free survival rate.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field