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Christos Vaklavas, Apostolia-Maria Tsimberidou, Sijin Wen, David Hong, Jennifer Wheler, Chaan S. Ng, Aung Naing, Cynthia Uehara, Robert A. Wolff and Razelle Kurzrock Phase 1 clinical trials in 83 patients with pancreatic cancer Cancer 117

Version of Record online: 24 AUG 2010 | DOI: 10.1002/cncr.25346

Of 83 patients with pancreatic cancer treated in the phase 1 program, the median survival duration from presentation in the phase 1 clinic was 5.0 months (95% confidence interval, 3.3-6.2), which compared favorably to the survival duration observed with best supportive care (3 months). The results suggest that phase 1 clinical trials offer a reasonable therapeutic approach for patients with advanced pancreatic cancer.

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